Hypertension Treatment — Explained Properly
Hypertension treatment aims for a home reading under 130/80 mmHg in most adults, using salt reduction, weight loss and one or more of an ACE inhibitor or ARB, a calcium channel blocker and a diuretic. Treatment is confirmed with home or 24-hour readings, and reviewed with kidney function, ECG and cardiac risk assessment.
How high blood pressure is actually treated: confirming the diagnosis with home readings, the baseline tests that must be done, how the four drug classes are chosen, when doses can be reduced, and what to do about resistant BP. From the practice of Dr. Sanjay Sachdev (MBBS, MNAMS), South Delhi.
Step 1 — confirm before you treat
One high clinic reading is not hypertension. Diagnosis rests on averaged home readings — twice daily for 5–7 days — or ambulatory monitoring. This also identifies white-coat hypertension (high in clinic, normal at home) and masked hypertension (the reverse, and more dangerous).
Step 2 — baseline tests, always
ECG, kidney function (urea, creatinine, eGFR), urine routine plus albumin-creatinine ratio, electrolytes, fasting glucose or HbA1c, lipid profile and thyroid. Young, severe or resistant cases add a secondary-cause screen: primary aldosteronism, renal artery stenosis, sleep apnoea, thyroid disease.
Step 3 — lifestyle that measurably moves BP
Salt below 5 g/day (roughly 10–12 mmHg in salt-sensitive patients), 7–10% weight loss, 150 minutes of weekly aerobic activity, potassium-rich diet unless kidney disease restricts it, alcohol reduction, and treating snoring or witnessed apnoea.
Step 4 — drug selection and combination
ACE inhibitors or ARBs for younger patients, diabetes and proteinuria; calcium channel blockers and thiazide-like diuretics for older patients; beta-blockers where there is angina, prior infarct, heart failure or arrhythmia. Low-dose two-drug single-pill combinations are preferred over maximum-dose monotherapy — better control, fewer side effects.
Step 5 — resistant hypertension
Still above target on three drugs including a diuretic? The review covers adherence, salt load, NSAIDs and steroids, decongestants, alcohol, sleep apnoea, renal artery disease and primary aldosteronism — before a fourth tablet (usually spironolactone) is added.
Step 6 — de-escalation and long-term review
Where weight loss and lifestyle change have held for 6–12 months, a supervised dose taper is offered with home BP monitoring. Otherwise review every 6 months with BP, weight, kidney function, electrolytes and a side-effect check.
Frequently asked
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